Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2009 2
2010 1
2012 1
2016 1
2018 2
2019 1
2020 2
2021 1
2022 1
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

12 results

Results by year

Filters applied: . Clear all
Page 1
Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias.
London B, Michalec M, Mehdi H, Zhu X, Kerchner L, Sanyal S, Viswanathan PC, Pfahnl AE, Shang LL, Madhusudanan M, Baty CJ, Lagana S, Aleong R, Gutmann R, Ackerman MJ, McNamara DM, Weiss R, Dudley SC Jr. London B, et al. Circulation. 2007 Nov 13;116(20):2260-8. doi: 10.1161/CIRCULATIONAHA.107.703330. Epub 2007 Oct 29. Circulation. 2007. PMID: 17967977 Free PMC article.
GPD1-L RNA and protein are abundant in the heart. Compared with wild-type GPD1-L, coexpression of A280V GPD1-L with SCN5A in HEK cells reduced inward Na+ currents by approximately 50% (P<0.005). Wild-type GPD1-L localized near the cell surfac …
GPD1-L RNA and protein are abundant in the heart. Compared with wild-type GPD1-L, coexpression of A280V GPD1-L w …
Genetic and clinical aspects of Brugada syndrome: an update.
Lippi G, Montagnana M, Meschi T, Comelli I, Cervellin G. Lippi G, et al. Adv Clin Chem. 2012;56:197-208. doi: 10.1016/b978-0-12-394317-0.00009-1. Adv Clin Chem. 2012. PMID: 22397033 Review.
BS is typically associated with a high risk for sudden cardiac death (SCD) in young and otherwise healthy adults. Although in several patients the heart is structurally normal, subtle structural abnormalities in the right ventricular outflow tract are increasingly been rep …
BS is typically associated with a high risk for sudden cardiac death (SCD) in young and otherwise healthy adults. Although in several patien …
A novel mutation in GPD1-L associated with early repolarization syndrome via modulation of cardiomyocyte fast sodium currents.
Fan J, Ji CC, Cheng YJ, Yao H, Chen XM, Zheng ZH, Wu SH. Fan J, et al. Int J Mol Med. 2020 Mar;45(3):947-955. doi: 10.3892/ijmm.2020.4454. Epub 2020 Jan 8. Int J Mol Med. 2020. PMID: 31922248
Whole-cell patch-clamp recording, confocal microscopic observation and western blotting were used to uncover the potential mechanism of GPD1-L P112L in ERS. The results of western blotting indicated that the expression of the GPD1-L protein was lower in the MT group …
Whole-cell patch-clamp recording, confocal microscopic observation and western blotting were used to uncover the potential mechanism of G …
Changes to PUFA-PPAR pathway during mesaconitine induced myocardial coagulative necrosis.
Chen Q, Deng X, Zhang K, Kang Y, Jiao M, Zhang J, Wang C, Li F. Chen Q, et al. Food Chem Toxicol. 2023 Jul;177:113831. doi: 10.1016/j.fct.2023.113831. Epub 2023 May 12. Food Chem Toxicol. 2023. PMID: 37182599
Coagulation necrosis is characterized by the denaturation of structural proteins and lysosomal enzymes; its occurrence in myocardium can lead to heart failure. Current studies on myocardial injury primarily focus on inflammation, hypertrophy, and hemorrhage, while those on …
Coagulation necrosis is characterized by the denaturation of structural proteins and lysosomal enzymes; its occurrence in myocardium can lea …
miR-409-3p Regulated by GATA2 Promotes Cardiac Fibrosis through Targeting Gpd1.
Wang C, Yin S, Wang Q, Jiang M, Li S, Zhen W, Duan Y, Gu H. Wang C, et al. Oxid Med Cell Longev. 2022 Oct 12;2022:8922246. doi: 10.1155/2022/8922246. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 36275896 Free PMC article.
Cardiac fibrosis is a hallmark of numerous chronic cardiovascular diseases that leads to heart failure. However, there is no validated therapy for it. Dysregulation of microRNAs has been confirmed to be involved in cardiac fibrosis development. ...On the contrary, the miR- …
Cardiac fibrosis is a hallmark of numerous chronic cardiovascular diseases that leads to heart failure. However, there is no validate …
DNA isolated from formalin-fixed paraffin-embedded healthy tissue after 30 years of storage can be used for forensic studies.
Vitošević K, Todorović M, Slović Ž, Varljen T, Matić S, Todorović D. Vitošević K, et al. Forensic Sci Med Pathol. 2021 Mar;17(1):47-57. doi: 10.1007/s12024-020-00327-z. Epub 2020 Nov 7. Forensic Sci Med Pathol. 2021. PMID: 33159288
The quality of isolated DNA was evaluated by PCR amplification of GPD1 (150 bp), ACTB (262 bp) and RPL4 (407 bp) genes. The histomorphological characteristics of FFPE tissues were not significantly changed during 30 years of storage. ...The PCI extraction method showed rep …
The quality of isolated DNA was evaluated by PCR amplification of GPD1 (150 bp), ACTB (262 bp) and RPL4 (407 bp) genes. The histomorp …
HIF-1α and PPARγ during physiological cardiac hypertrophy induced by pregnancy: Transcriptional activities and effects on target genes.
Soñanez-Organis JG, Godoy-Lugo JA, Hernández-Palomares ML, Rodríguez-Martínez D, Rosas-Rodríguez JA, González-Ochoa G, Virgen-Ortiz A, Ortiz RM. Soñanez-Organis JG, et al. Gene. 2016 Oct 15;591(2):376-81. doi: 10.1016/j.gene.2016.06.025. Epub 2016 Jun 14. Gene. 2016. PMID: 27312951
Expressions of mRNA for glucose transport 1 (GLUT1), enzymes of glycolysis (HK2, PFKM, and GAPDH) and glycerol-lipid biosynthesis (GPAT and GPD1) increased 1.6- to 14-fold during pregnancy and returned to basal levels postpartum. The increase in GPD1 expression tran …
Expressions of mRNA for glucose transport 1 (GLUT1), enzymes of glycolysis (HK2, PFKM, and GAPDH) and glycerol-lipid biosynthesis (GPAT and …
Effect of formalin fixation on pcr amplification of DNA isolated from healthy autopsy tissues.
Vitošević K, Todorović M, Varljen T, Slović Ž, Matić S, Todorović D. Vitošević K, et al. Acta Histochem. 2018 Nov;120(8):780-788. doi: 10.1016/j.acthis.2018.09.005. Epub 2018 Sep 15. Acta Histochem. 2018. PMID: 30224244
The PCR amplifications of the glycerol-3-phosphate dehydrogenase 1 (GPD1, 150 bp), ss actin (ACTB, 262 bp) and ribosomal protein L4 (RPL4, 407 bp) genes were performed to evaluate the degree of DNA fragmentation. The RPL4 gene was amplified up to 72 h, ACTB gene up to 14 d …
The PCR amplifications of the glycerol-3-phosphate dehydrogenase 1 (GPD1, 150 bp), ss actin (ACTB, 262 bp) and ribosomal protein L4 ( …
Cardiac Na+ current regulation by pyridine nucleotides.
Liu M, Sanyal S, Gao G, Gurung IS, Zhu X, Gaconnet G, Kerchner LJ, Shang LL, Huang CL, Grace A, London B, Dudley SC Jr. Liu M, et al. Circ Res. 2009 Oct 9;105(8):737-45. doi: 10.1161/CIRCRESAHA.109.197277. Epub 2009 Sep 10. Circ Res. 2009. PMID: 19745168 Free PMC article.
The influence of NADH/NAD+ on arrhythmic risk was evaluated in wild-type or SCN5A(+/-) mouse heart. A280V GPD1-L caused a 2.48+/-0.17-fold increase in intracellular NADH level (P<0.001). ...Increasing intracellular NADH was associated with an increased risk of ve …
The influence of NADH/NAD+ on arrhythmic risk was evaluated in wild-type or SCN5A(+/-) mouse heart. A280V GPD1-L caused a 2.48 …
GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A.
Valdivia CR, Ueda K, Ackerman MJ, Makielski JC. Valdivia CR, et al. Am J Physiol Heart Circ Physiol. 2009 Oct;297(4):H1446-52. doi: 10.1152/ajpheart.00513.2009. Epub 2009 Aug 7. Am J Physiol Heart Circ Physiol. 2009. PMID: 19666841 Free PMC article.
The SCN5A-encoded cardiac sodium channel underlies excitability in the heart, and dysfunction of sodium current (I(Na)) can cause fatal ventricular arrhythmia in maladies such as long QT syndrome, Brugada syndrome (BrS), and sudden infant death syndrome (SIDS). ...Because …
The SCN5A-encoded cardiac sodium channel underlies excitability in the heart, and dysfunction of sodium current (I(Na)) can cause fat …
12 results